Certificate of Analysis (COA)
Notice
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
What is a Certificate of Analysis?
A Certificate of Analysis (COA) is an official document issued by the peptide manufacturer that accompanies each batch of product and provides detailed analytical data confirming the peptide's identity, purity, and quality. The COA serves as verifiable proof that the peptide has been tested using validated analytical methods and meets or exceeds the stated specifications. For researchers, reviewing the COA before beginning experiments is an essential step in ensuring that their peptide reagents are suitable for the intended application.
What Information Does a COA Contain?
- Product Name and Catalog Number: Identifies the specific peptide and batch.
- Batch/Lot Number: A unique identifier for traceability.
- Amino Acid Sequence: The full sequence of the peptide, confirming its identity.
- Molecular Weight: Both theoretical and observed (via mass spectrometry).
- HPLC Purity: The percentage purity determined by high-performance liquid chromatography, often with the chromatogram included.
- Mass Spectrometry Data: The observed mass confirming the molecular identity.
- Appearance: Physical description of the lyophilized product (e.g., white powder).
- Storage Conditions: Recommended storage temperature and handling instructions.
Why the COA Matters for Research
The COA is a critical quality document that enables researchers to verify that their peptides are authentic, pure, and correctly manufactured before incorporating them into experiments. Without a COA, there is no independent verification that the peptide in the vial matches what was ordered. Reputable suppliers like Pure U.S. Peptides provide a comprehensive COA with every order, including raw HPLC chromatograms and mass spectrometry spectra, giving researchers full transparency into the quality of their reagents.