Bioregulators
Notice
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
What Are Bioregulators?
Bioregulators, also known as bioregulatory peptides or Khavinson peptides (named after Professor Vladimir Khavinson, who pioneered their research), are ultra-short peptide sequences typically composed of just 2 to 4 amino acids. These small peptides are studied for their ability to penetrate cell membranes, interact with specific DNA sequences, and modulate gene expression in a tissue-specific manner. Unlike larger peptides that typically act by binding to cell-surface receptors, bioregulators are hypothesized to work at the epigenetic level, influencing how genes are read and expressed within specific cell types.
How Bioregulators Are Studied
Research into bioregulators focuses on their potential to interact with the promoter regions of specific genes. In vitro studies using cell culture models have examined how these short peptide sequences may influence protein synthesis, cell proliferation, and cellular differentiation. Due to their very small molecular weight (typically under 500 Da), bioregulators present interesting pharmacokinetic properties, including relatively high stability and the theoretical ability to cross cell membranes without specialized transport mechanisms. The field remains an active area of investigation, with ongoing studies exploring the specificity and mechanisms of these peptide-DNA interactions.
Categories of Bioregulators
Bioregulators are often classified according to the tissues or organ systems they have been studied in relation to. Examples studied in the research literature include peptides investigated for their interactions with thymic tissue, pineal gland cells, vascular endothelium, retinal tissue, and various other organ-specific cell types. Each bioregulator is characterized by its unique amino acid sequence and the specific gene promoter regions it has been observed to interact with in experimental settings.
Research Considerations
As with all research peptides, bioregulators available from Pure U.S. Peptides are intended exclusively for in vitro laboratory research. The quality and purity of bioregulatory peptides is especially important because their extremely short sequences mean that even minor impurities could represent a significant molar fraction of the total sample. All bioregulator peptides undergo the same rigorous HPLC and mass spectrometry testing as longer peptides, with complete analytical documentation provided in the Certificate of Analysis for each batch.