BPC-157
The connective-tissue research workhorse Paradigm customers ordered most often. Pure U.S. Peptides carries BPC-157 10mg with a public per-batch HPLC certificate of analysis on the product page.
View product →Paradigm Peptides Shut Down — Where Researchers Are Going Now
Paradigm Peptides closed following a federal criminal case. Owners Matthew Kawa and Jennifer Stechkober pleaded guilty December 10, 2025; Matthew Kawa was sentenced March 24, 2026. The site now displays a closure notice and the owners cannot lawfully return. Below: direct top-SKU swaps for former Paradigm researchers, sourced from a research-only U.S. supplier.
Top SKU swaps — what former Paradigm researchers are reordering
TB-500
Paradigm's second most-searched compound by historical brand-search volume. Pure U.S. Peptides carries TB-500 10mg, U.S.-fulfilled, with public per-batch COA.
View product →Ipamorelin
A selective ghrelin-receptor research compound, regularly stocked in the Paradigm catalog. Pure U.S. Peptides carries Ipamorelin 10mg with HPLC verification.
View product →Selank
A synthetic tuftsin-analog research peptide. Pure U.S. Peptides carries Selank 10mg with public per-batch COA.
View product →Semax
An ACTH(4-10)-fragment research peptide. Pure U.S. Peptides carries Semax 30mg with public per-batch COA.
View product →What we can say about the closure
Paradigm Peptides is closed. According to the U.S. Department of Justice press release for the Northern District of Indiana, the company's owners pleaded guilty to federal charges on December 10, 2025, and Matthew Kawa was sentenced March 24, 2026. The original owners are criminally enjoined from returning to this product category, and there is no public DOJ filing indicating an authorized relaunch under any name.
For the official source, see the U.S. Department of Justice press release. For a longer-form explainer see What Happened to Paradigm Peptides, and for the full alternative comparison see Paradigm Peptides Alternative.
Researchers should be cautious of any "new Paradigm" site. A federally closed brand is a common target for scam relaunches. If you receive an unsolicited email or advertisement claiming Paradigm Peptides has reopened, do not enter payment information without independent verification.
What former Paradigm researchers are looking for in a replacement
- U.S.-based fulfillment. Domestic warehouse, same-day shipping, no import-seizure risk.
- Public per-batch COAs. Lot-specific certificate of analysis from an independent U.S. lab, published on each product page — not behind an email request form.
- Tight research-only catalog. A focused catalog of workhorse research molecules, with no drift into product categories that attract heightened regulatory scrutiny.
- Standard payment methods. Major-card checkout, Zelle, Venmo, and Cash App — not crypto-only.
Pure U.S. Peptides — research-only, U.S.-fulfilled
32 HPLC-verified research compounds with public per-batch COAs. Use code PARADIGMSWITCH25 for 20% off your first order.
Browse the catalog →Research Use Only. All compounds sold by Pure U.S. Peptides are intended exclusively for in-vitro research and laboratory use by qualified investigators. They are not intended for human or veterinary consumption.
Educational content. This page summarizes facts cited from the U.S. Department of Justice press release for the Northern District of Indiana. Pure U.S. Peptides has no business relationship with Paradigm Peptides, Matthew Kawa, or Jennifer Stechkober, and no involvement in the underlying federal case. The DOJ citation is for context only.