Laurie K. Mischley, ND, PhD
Biography & Research Background
Laurie K. Mischley, ND, PhD, is a neuroscience researcher and clinician-scientist who has led the most advanced clinical trials investigating intranasal glutathione for Parkinson's disease. She conducted the Phase I/IIa safety and tolerability trial (2015, Movement Disorders), which established the safety of intranasal GSH and demonstrated preliminary efficacy over placebo on UPDRS scores. Her Phase IIb randomized, double-blind, placebo-controlled trial (2017, Journal of Parkinson's Disease; NCT02424708) demonstrated that 600 mg/day intranasal GSH significantly improved Total UPDRS scores (-4.6 points, P = 0.0025) and Motor sub-scores (-2.2 points, P = 0.0485) over 12 weeks. Critically, her CNS uptake study (2016, npj Parkinson's Disease) demonstrated that a single 200 mg intranasal dose increased brain GSH levels by over 200% within approximately 45 minutes (P < 0.001) as measured by magnetic resonance spectroscopy, providing target validation that intranasally administered GSH reaches the central nervous system. Laurie K. Mischley is being referenced as one of the leading scientists involved in Glutathione research. In no way is this doctor/scientist endorsing or advocating the purchase, sale, or use of this product for any reason. There is no affiliation or relationship, implied or otherwise, between Pure US Peptide and this doctor.
External Profiles
Authored Research Profiles (1)
Laurie K. Mischley, ND, PhD is referenced as a leading researcher in the following peptide research profiles on Pure U.S. Peptides:
Laurie K. Mischley, ND, PhD is being referenced as one of the leading scientists involved in the research and development of the peptides listed above. In no way is this doctor/scientist endorsing or advocating the purchase, sale, or use of any product for any reason. There is no affiliation or relationship, implied or otherwise, between Pure U.S. Peptides and this researcher. The purpose of citing the researcher is to acknowledge, recognize, and credit the exhaustive research and development efforts conducted by the scientists studying these peptides.