Sermorelin: Safety Profile & Research Summary
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Buy Sermorelin Peptide 10mgClinical Studies
ποΈ Sermorelin is the classic GHRH fragment β formerly FDA-registered (as Geref) for pediatric and diagnostic use. That former registration does not apply to this research-grade material.
| Study | Type | n= | Indication |
|---|---|---|---|
| Khorram 1997 (Metabolic) | RCT | 19 | Healthy Elderly |
| Khorram 1997 (Immune) | RCT | 19 | Healthy Elderly |
| Vittone 1997 | Prospective | 11 | Elderly Men |
| Corpas 1992 | Dose-ranging | 19 | Young vs Elderly |
| Sigalos 2017 | Retrospective | 14 | Hypogonadal Men |
| Thorner 1996 (Geref ISG) | Multicenter OL | 110 | Pediatric GHD |
| Diagnostic literature | Provocative test | β | Pituitary Function |
| Veldhuis 2008 | Physiology | 22 | GH Burst Waveform |
Handling Safety
Handle with standard laboratory PPE. Consult the SDS.
Regulatory note: FDA confirmed Geref was NOT withdrawn for tolerability or efficacy reasons. [4]
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
βClinical Studies ποΈ Sermorelin is the classic GHRH fragment β formerly FDA-registered (as Geref) for pediatric and diagnostic use.β
References
- Chang Y, Huang R, Zhai Y, et al. Ann Transl Med, 9(5), 406, 2021.
- Prakash A, Goa KL. BioDrugs, 12(2), 139-157, 1999.
- Walker RF. Clin Interv Aging, 1(4), 307-308, 2006.
- Food and Drug Administration. Fed Register, 78(42), 14095-14096, 2013.
- Sinha DK, Balasubramanian A, Tatem AJ, et al. Transl Androl Urol, 9(Suppl 2), S149-S159, 2020.
- Grossman AB, Savage MO, Lytras N, Besser GM. Clin Endocrinol (Oxf), 21(3), 321-330, 1984.
- Corpas E, Harman SM, PiΓ±eyro MA, et al. J Clin Endocrinol Metab, 75(2), 530-535, 1992.
- Heiman ML, Nekola MV, Murphy WA, Lance VA, Coy DH. An extremely sensitive in vitro model for elucidating structure-activity relationships of growth hormone-releasing factor analogs. Endocrinology, 116(1), 410-415, 1985.
- Gelander L, Lindstedt G, Selstam G, et al. Horm Res, 31(5-6), 213-220, 1989.
- Khorram O, Laughlin GA, Yen SS. J Clin Endocrinol Metab, 82(5), 1472-1479, 1997.
- Khorram O, Yeung M, Vu L, Yen SS. J Clin Endocrinol Metab, 82(11), 3590-3596, 1997.
- Vittone J, Blackman MR, Busby-Whitehead J, et al. Metabolism, 46(1), 89-96, 1997.
- Vitiello MV, Schwartz RS, Moe KE, Mazzoni G, Merriam GR. Dialogues Clin Neurosci, 3(3), 229-236, 2001.
- Sigalos JT, Pastuszak AW, Allison A, et al. Am J Mens Health, 11(6), 1752-1757, 2017.
- Schally AV, Wang H, He J, et al. PNAS, 115(47), 12028-12033, 2018.
- Jaszberenyi M, Rick FG, Popovics P, et al. Potentiation of cytotoxic chemotherapy by growth hormone-releasing hormone agonists. PNAS, 111(2), 781-786, 2014.
- Soule SG, King JA, Millar RP. J Clin Endocrinol Metab, 79(4), 1208-1211, 1994.
- Merriam GR, Buchner DM, Prinz PN, Schwartz RS, Vitiello MV. Endocrine, 7(1), 49-52, 1997.
- Walker RF, Yang SW, Bercu BB. Robust Growth Hormone (GH) secretion in aged female rats co-administered GH-releasing hexapeptide (GHRP-6) and GH-releasing hormone (GHRH). Life Sci, 49(20), 1499-1504, 1991.
- Rafferty B, Coy DH, Poole S. Pharmacokinetic evaluation of superactive analogues of growth hormone-releasing factor (1-29)-amide. Peptides, 9(1), 207-209, 1988.
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This content is provided for educational and informational purposes only. Products are furnished for in-vitro studies only and are not medicines, drugs, or supplements. Not approved by the FDA to prevent, treat, or cure any condition.