ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
<p class="mb-4"> The copper peptide GHK-Cu is unique among regenerative agents because its effects appear to be largely epigenetic. It does not merely stimulate a receptor; it modulates the expression of thousands of human genes, essentially pressing a "reset button" on cells to return them to a more youthful metabolic state. </p> <p> Greenfield et al. (2018) analyzed the effect of GHK on gene expression using genomic databases and found that it induces a signature that opposes aging—suppressing tissue destruction and inflammation while upregulating repair. Furthermore, Pickart (2018) highlighted its role in skin biology, where it facilitates tight remodeling by balancing collagen breakdown and synthesis, leading to improved barrier repair and reduced oxidative stress. </p>
The copper peptide GHK-Cu is unique among regenerative agents because its effects appear to be largely epigenetic. It does not merely stimulate a receptor; it modulates the expression of thousands of human genes.
Greenfield et al. (2018) utilized the Connectivity Map (a genomic database) to analyze the effect of GHK on gene expression. The findings were remarkable: GHK induces a gene expression signature that opposes aging. It suppresses genes involved in tissue destruction and inflammation while upregulating genes associated with tissue repair and antioxidant defense.
This explains why GHK-Cu is often described as pressing a "reset button" on cells, returning them to a more youthful metabolic state.
Pickart and Margolina (2018) reviewed GHK's role in skin biology. The peptide facilitates tight skin remodeling by balancing the breakdown of old collagen (via metalloproteinases) with the synthesis of new, organized collagen.
GHK-Cu serves as a master regulator of tissue health, bridging the gap between simple nutrition (copper transport) and complex genetic regulation.
