Storing ARA-290: Best Practices
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Comprar peptídeo ARA-290 10mg (Cibinetide)❄️ Liofilizado Powder Storage
Liofilizado ARA-290 is estável à temperatura ambiente during shipping but deve ser armazenado longo prazo at −20°C (−4°F) or lower onde it remains estavel por até 3 years, or at 2–8°C (36–46°F) por até 2 years. Proteja da luz em todos os momentos.
🧴 Handling Precautions
Práticas laboratoriais padrão tolerability practices apply. ARA-290 is apenas para uso em pesquisa (RUO). O certificado de lote deste produto está pendente.
“Estudos em Animais Dor Neuropatica (Ratos): 30–60 µg/kg IP produziu alivio dose-dependentee e de longo prazo (20 semanas) da alodinia mecanica e ao frio com supressao da ativacao da microglia espinhal.”
Referencias
- Winicki NM, Nanavati AP, Morrell CH, et al. A pequeno(a) erythropoietin derived non-hematopoietic peptide reduz inflamacao cardiaca, atenua age associated declines in heart function and prolongs healthspan. Front Cardiovasc Med, 9, 1096887, 2023.
- Brines M, Patel NS, Villa P, et al. Nonerythropoietic, protetor(a) de tecidos peptides derivado(a) de the tertiary structure of erythropoietin. PNAS USA, 105(31), 10925–10930, 2008.
- Swartjes M, Morariu A, Niesters M, et al. Anesthesiology, 115(5), 1084–1092, 2011.
- Dahan A, Dunne A, Swartjes M, et al. Mol Med, 19(1), 334–345, 2013.
- Brines M, Dunne AN, van Velzen M, et al. Mol Med, 20(1), 658–666, 2015.
- Heij L, Niesters M, Swartjes M, et al. Mol Med, 18(1), 1430–1436, 2012.
- Swartjes M, van Velzen M, Niesters M, et al. Mol Pain, 10, 13, 2014.
- McVicar CM, Hamilton R, Colhoun LM, et al. Intervention with an erythropoietin-derived peptide protege against neuroglial and vascular degeneration during diabetic retinopatia. Diabetes, 60(11), 2995–3005, 2011.
- Culver DA, Dahan A, Bajorunas D, et al. Invest Ophthalmol Vis Sci, 58(6), BIO52–BIO60, 2017.
- Lois N, Gardner E, McFarland M, et al. J Clin Med, 9(7), 2225, 2020.
- Nairz M, Haschka D, Dichtl S, et al. Cibinetide dampens innate immune cell functions thus ameliorating o curso of experimental colitis. Sci Rep, 7(1), 13012, 2017.
- Collino M, Benetti E, Rogazzo M, et al. A non-erythropoietic peptide derivative of erythropoietin diminui susceptibility to diet-induziu resistencia a insulina in mice. Br J Pharmacol, 171(24), 5802–5815, 2014.
- Tokodai K, Brines M, Ericzon BG, et al. Improvement of Islet Allograft Function Using Cibinetide, an Innate Repair Receptor Ligand. Transplantation, 104(10), 2020.
- Kumagai-Braesch M, Cerami A, Ericzon BG, et al. Cell Transplantation, 30, 2021.
- Schmidt RE, Feng D, Wang Q, et al. Effect of insulin e um(a) erythropoietin-derived peptide (ARA290) on estabeleceu neuritic dystrophy in Akita diabetic mouse sympathetic ganglia. Exp Neurol, 232(2), 126–135, 2011.
- Niesters M, Swartjes M, Heij L, et al. Expert Opin Orphan Drugs, 1, 77–87, 2013.
- Pulman KG, Smith M, Mengozzi M, et al. The erythropoietin-derived peptide ARA290 reverses mechanical allodynia no(a) neuritis model. Neuroscience, 233, 174–183, 2013.
- Brines M. Discovery of a Master Regulator of Injury and Healing: Tipping the Outcome from Damage toward Repair. Mol Med, 20(Suppl 1), S10–S16, 2014.
- Ahmet I, Tae H, Brines M, et al. Chronic administration of pequeno(a) nonerythropoietic peptide of erythropoietin melhora postinfarto do miocardio-dilated cardiomiopatia. J Pharmacol Exp Ther, 345(3), 446–456, 2013.
- Coldewey SM, Khan AI, Kapoor A, et al. Kidney Int, 84(3), 482–490, 2013.
- Muller C, Yassin K, Li LS, et al. ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats. Mol Med, 21(1), 969–978, 2016.
Perguntas de Pesquisa Relacionadas
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Comprar peptídeo ARA-290 10mg (Cibinetide)→APENAS PARA USO EM PESQUISA
Este conteudo e fornecido apenas para fins educacionais e informativos. Os produtos sao fornecidos apenas para estudos in vitro e nao sao medicamentos, drogas ou suplementos. Nao aprovado pela FDA para prevenir, tratar ou curar qualquer condicao.
