Storing Retatrutide: Best Practices

Lyophilized Powder

Store at -80°C for optimal long-term stability (approximately 2 years) or at -20°C for up to 1 year. Keep in sealed containers, protected from moisture and light, ideally under nitrogen atmosphere. The lyophilized form appears as a white to off-white solid powder.

Reconstituted Solution

Dissolve in sterile water (soluble at 20 mg/mL with pH adjustment) or DMSO. Prepare working aliquots immediately upon reconstitution to prevent repeated freeze-thaw cycles, which can inactivate the peptide. Store aliquots at -20°C and use within 1 month for best results.

Quality Control

Purity is assessed by RP-HPLC (targeting ≥99% for research grade). Molecular identity is confirmed by Mass Spectrometry (expected MW ~4731.33 Da). Additional characterization may include NMR spectroscopy (H-NMR) for structural verification. The C20 fatty diacid conjugation at Lys-17 enhances metabolic stability in biological systems.